Study: Marijuana Use Linked to Lower Prevalence of Fatty Liver Disease

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NORML | May 4, 2017

LOWELL, MA — Subjects who consume cannabis are significantly less likely to suffer from non-alcoholic fatty liver disease (NAFLD) as compared to those who do not, according to population-based case-control data published in the journal PLOS One.

Non-alcoholic fatty liver disease is the most prevalent form of liver disease in humans, affecting an estimated 80 to 100 million people in the United States.

A team of researchers from the University of Massachusetts Medical School…

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Study: Cannabis Use Associated With Decreased Crack Cocaine Consumption

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VANCOUVER, BC — Cannabis consumption is positively associated with the decreased use of crack cocaine, according to longitudinal data published in the journal Addictive Behaviors.

Canadian investigators assessed the use patterns of cannabis and crack cocaine in a cohort of 122 subjects over a three-year period. They reported that participants subsequently reduced their frequency of crack cocaine consumption following the intentional use of cannabis.

They concluded: “In this longitudinal study, we observed that a period of…

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Study: Cannabis Often Substituted for Prescription Medications

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Paul Armentano | May 3, 2017

Adults often substitute cannabis for the use of prescription medications, according to data published in the Journal of Pain Research.

Investigators from the Bastyr University Research Institute assessed the frequency of drug substitution among a self-selected national sample of 2,774 self-identified marijuana consumers.

Just under half of respondents (46 percent) reported using cannabis in place of prescription medications. Respondents were most likely to use cannabis in lieu of…

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Can Decriminalizing Marijuana Lead to Higher Wages? Study Says Yes.

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(Flickr/neetalparekh)

NORML | April 27, 2017

IRVINE, CA — Reducing criminal penalties for marijuana offenses is associated with greater overall employment and higher wages, according to data compiled by economists at the University of California.

Researchers at the Economic Self-Sufficiency Research Policy Institute at the University of California at Irvine assessed the relationship between statewide marijuana decriminalization laws and labor outcomes.

Authors reported that decriminalization is…

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Study: Medical Marijuana Legalization Linked to Lower Medicaid Costs

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(Sonya Yruel/Drug Policy Alliance)

Paul Armentano | April 21, 2017

Patients use fewer prescription drugs in states where access to medical cannabis is legally regulated, according to data published in the journal Health Affairs.

Investigators at the University of Georgia assessed the association between medical cannabis regulations and the average number of prescriptions filled by Medicaid beneficiaries between the years 2007 and 2014.

Researchers reported, “[T]he use of prescription drugs in…

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Study: Medical Cannabis Patients Report Decreased Use of Opioids, Anti-Anxiety Medicines

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NORML | April 13, 2017

SCRANTON, PA — Patients with legal access to medical cannabis decrease their use of opioids, anti-depressants, anti-anxiety drugs, and other medications, according to self-report data published online ahead of print in the Journal of Psychopharmacology.

A team of investigators from five states surveyed the medical history of over 1,500 patient-members of state-licensed dispensaries located throughout the northeast.

Authors reported that 77 percent of respondents…

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Marijuana Use Not Implicated in Injuries Requiring Hospitalization

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NORML | April 6, 2017

The use of marijuana alone does not place subjects at a higher risk of experiencing injuries requiring hospitalization, according to case-control data published in the journal Drug and Alcohol Dependence.

Investigators from the United States and Canada assessed the risk of injury in the hours immediately following subjects’ use of alcohol or other controlled substances.

Researchers determined that alcohol use within the past six hours significantly increased subjects’…

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Study: Regular Cannabis Use Associated With Lower BMI, No Adverse Effect On Bone Density

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NORML | March 23, 2017

PORTLAND, OR — Those subjects who consume cannabis more than five times per month possess, on average, lower body mass index (BMI) than do those who do not use the substance, according to data published online ahead of print in the journal Archives of Osteoporosis.

Researchers at Oregon’s Health and Science University assessed the relationship between cannabis use and a variety of health outcomes in a nationally representative sample of 4,743 participants between the ages…

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Patients With Access to Medical Marijuana Reduce Their Use of Opioids, Study Finds

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Paul Armentano | March 16, 2017

ALBUQUERQUE, NM — Patients registered to use medical cannabis decrease their use of opioids, according to data compiled by researchers at the University of New Mexico.

Investigators assessed the use of prescription opioids over an 18-month period among patients enrolled in the state’s medical marijuana program compared to similar patients who were not.

They reported that subjects with access to medical cannabis reduced their use of opioids by 31 percent while…

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Study: CBD-Dominant Cannabis Extracts Reduce Seizure Frequency

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NORML | March 9, 2017

FALMOUTH, ME —  The administration of whole-plant cannabis extracts rich in the cannabinoid cannabidol (CBD) is associated with reduced seizure frequency in patients with refractory epilepsy, according to data published online ahead of print in the journal Epilepsy & Behavior.

Researchers performed a retrospective chart review of the clinical records of 272 patients who were taking whole-plant CBD extracts.

Eighty-six percent of those treated observed some clinical benefit…

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Medical Marijuana Legalization Associated with Fewer Opioid-Related Hospitalizations

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NORML | March 9, 2017

SAN DIEGO, CA — The enactment of statewide legislation permitting medical cannabis access by qualified patients is associated with a reduction in opioid-related hospitalization, according to data published online ahead of print in the journal Drug and Alcohol Dependence.

A researcher from the University of California at San Diego assessed the association between medical cannabis laws and hospitalizations related to opioid pain relievers. The author reported both immediate…

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Study: Marijuana Use Stable In Colorado Post-Legalization

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Paul Armentano | March 2, 2017

DENVER, CO — The percentage of Coloradoans who report using cannabis has remained relatively unchanged following the regulation of the adult use market, according to data published online ahead of print in the journal Preventive Medicine.

Researchers at the Colorado Department of Public Health and Environment reviewed statewide marijuana use data from January 1, 2014.

They reported:

“[M]arijuana use, both among adults and among youth, does not appear to be…

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Medical Marijuana Legalization Does Not Lead to Crime Increase

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Paul Armentano | February 24, 2017

WELLINGTON, NEW ZEALAND — The enactment of US laws regulating the sale and use of cannabis for medical purposes is not associated with any uptick in the rate of violent crime or property crime, according to data compiled by researchers at the University of Victoria and the Motu Economic and Public Policy Research Institute in New Zealand.

Investigators analyzed FBI crime data from the years 1988 to 2013 to assess the potential impact of medical marijuana…

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Study: Long Term Marijuana Use Doesn’t Increase Risk of Cardiovascular Disease

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Paul Armentano | February 24, 2017

BETHESDA, MD — Those who consume cannabis long-term suffer no greater likelihood of cardiovascular disease by middle age than do those with no history of use, according to longitudinal data published online ahead of print in the American Journal of Public Health.

An international team of researchers from the United States and Switzerland assessed cumulative cannabis use and cardiovascular risk in a cohort of over 5,000 subjects over a period of more than two decades. Authors…

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Study: Medical Marijuana Patients Reduce Their Use of Opioids

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Paul Armentano | February 16, 2017

VICTORIA, BC — Patients with legal access to medical cannabis reduce their use of opioids, benzodiazepines, and other prescription drugs, according to data published online ahead of print in The International Journal of Drug Policy.

Researchers at the University of Victoria and the University of British Columbia assessed the use of medical cannabis and prescription drugs in a cohort of 277 patients registered in the Canadian government’s medical marijuana…

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Study: Cannabis Extract Associated with Improved Survival Rates in Glioma Patients

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Glioma in the left parietal lobe (brain CT scan), WHO grade 2. (Wikimedia/Mikhail Kalinin)

NORML | February 9, 2017

LONDON — Brain tumor patients treated with cannabis extracts possessed increased one-year survival rates compared to those who went untreated, according to clinical trial data reported this week by British biotechnology firm GW Pharmaceuticals.

Twenty-one patients with recurrent glioblastoma multiforme and who were undergoing conventional anti-cancer treatment participated in the…

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Clinical Trial: THCV Lowers Blood Sugar Levels In Type 2 Diabetics

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Paul Armentano | January 26, 2017

DERBY, UK — The administration of THCV (tetrahydrocannabivarin), a non-psychoactive component of cannabis, is positively associated with glycemic control in type 2 diabetics, according to the randomized, placebo-controlled data published in the journal Diabetes Care.

Investigators from the University of Nottingham, School of Medicine assessed the twice daily administration of various cannabinoids (CBD or THCV or CBD and THCV in combination) versus placebo over a…

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National Academy of Sciences Releases Report on Marijuana Confirming Medical Benefits; Dispelling Myths

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Marijuana Policy Project | January 12, 2017

WASHINGTON, DC — The National Academies of Sciences, Engineering, and Medicine released a report on the health impacts of marijuana Thursday, confirming the existence of medical benefits and dispelling some long-held myths about the substance.

The review of more than 10,000 scientific abstracts found, “There is conclusive or substantial evidence that cannabis or cannabinoids are effective” for the treatment of chronic pain in adults, chemotherapy-induced nausea…

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NORML Responds to National Academy of Sciences’ Marijuana Report

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NORML | January 12, 2017

WASHINGTON, DC — The National Academy of Sciences, Engineering, and Medicine released a comprehensive report Thursday acknowledging that “conclusive or substantial evidence” exists for cannabis’ efficacy in patients suffering from chronic pain, and sharply criticized longstanding federal regulatory barriers to marijuana research – in particular “the classification of cannabis as a Schedule I substance” under federal law.

Authors of the report also addressed…

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Study: History of Cannabis Use Not An Independent Risk Factor for Stroke

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NORML | January 12, 2017

STOCKHOLM, SWEDEN — The use of cannabis is not an independent contributing factor to the risk of stroke in those under 60 years of age, according to population-based data published online ahead of print in the journal Stroke.

An international team of investigators from Sweden and France assessed the relationship between marijuana use and stroke risk in a population-based cohort of over 49,000 men.

Researchers reported “no significant association between cannabis use in…

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Most Police Want Marijuana Laws Reformed, Poll Finds

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TJ Baker | January 11, 2017

In a national poll of police officers conducted on a wide variety of topics, less than one third of those surveyed said marijuana should remain illegal.

According to the Behind the Badge survey of nearly 8,000 police officers conducted by the National Police Research Platform (NPRP), 68% of police support legalizing medical marijuana.

While 32 percent of police surveyed supported full legalization of marijuana for adults, the number is still lower than the national…

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Study: Medical Marijuana Laws Associated With Fewer Traffic Fatalities

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Paul Armentano | December 21, 2016

The passage of medical marijuana legalization is associated with reduced traffic fatalities among younger drivers, according to data published online ahead of print in the American Journal of Public Health.

Investigators from Columbia University in New York and the University of California at Davis analyzed traffic fatality data from the years 1985 to 2014.

They reported that states with medical cannabis laws had lower overall traffic fatality rates compared to…

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Study: History of Marijuana Use Helps Reduce In-Hospital Mortality

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Paul Armentano | December 8, 2016

GREELEY, CO — Hospitalized patients who test positive for cannabis are less likely than non-users to suffer from heart failure or cardiac disease, and are less likely to die from cancer, according to data published online ahead of print in the journal Cancer Medicine.

A team of researchers from the University of Northern Colorado, Colorado State University, and the University of Alabama assessed the relationship between marijuana use and health outcomes among a…

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Recreational Marijuana Use is Increasing Among Adults Over 50

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(Darrin Harris Frisby/Drug Policy Alliance)

(Darrin Harris Frisby/Drug Policy Alliance)

TJ Baker | December 5, 2016

Baby Boomers are quickly becoming the largest generation to admit to marijuana use after age 50, according to a new study released by New York University.

There is a common misperception that widespread marijuana use is limited to younger generations,” researchers write.  “However, the Baby Boomer generation has reported higher rates of substance use than any preceding generation.”

“Given the unprecedented aging of the U.S….

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More Medical Marijuana Patients Using Vaporizers, Studies Find

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A woman uses a vaporizer to medicate with cannabis. (Sonya Yruel/Drug Policy Alliance)

A woman uses a vaporizer to medicate with cannabis. (Sonya Yruel/Drug Policy Alliance)

Paul Armentano | December 1, 2016

Medical marijuana patients are increasingly turning to vaporization as their preferred means of cannabis delivery, according to survey data published in Drug and Alcohol Dependence and in the Harm Reduction Journal.

In one study, investigators from the University of Waterloo, School of Public Health surveyed the consumption habits of 364 patients registered in Canada’s medical marijuana…

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Medical Marijuana Legalization Doesn’t Drive Teens to Pot Use: Study

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medical marijuana - rolling a joint

Paul Armentano | December 1, 2016

State laws regulating the use and dispensing of medical marijuana are not associated with increased cannabis use rates among young people, according to findings published online ahead of print in the journal Drug and Alcohol Dependence.

Researchers at Brandeis University and Harvard Medical School assessed adolescent marijuana use patterns in 45 states between the years 1991 to 2011. Authors reported “little evidence for an increase in past-30-day marijuana use,…

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Study: Medical Cannabis Use Associated With Improved Cognitive Performance, Reduced Use Of Opioids

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painkillers vs marijuana

Paul Armentano | November 14, 2016

Medical cannabis administration is associated with improved cognitive performance and lower levels of prescription drug use, according to longitudinal data published online in the journal Frontiers in Pharmacology.

Investigators from Harvard Medical School, Tufts University, and McLean Hospital evaluated the use of medicinal cannabis on patients’ cognitive performance over a three-month period. Participants in the study were either naïve to cannabis or had abstained from the…

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Reforming Marijuana Laws Doesn’t Increase Youth Usage, Two Studies Find

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lighting a smoking joint

NORML | November 4, 2016

Changes in marijuana’s legal status under state law is not associated with increased cannabis use or access by young people, according to pair of recently published studies.

In the first study, published online in the journal Substance Use & Misuse, researchers at Columbia University in New York surveyed the marijuana use habits of a national sampling of 1,310 adolescents over a two-year period. Investigators assessed whether respondents from states with liberalized cannabis…

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Study: Cannabis Use By Seniors On The Rise

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(Sonya Yruel/Drug Policy Alliance)

(Sonya Yruel/Drug Policy Alliance)

Paul Armentano | November 3, 2016

NEW YORK, NY — Self-reported marijuana use by those age 50 and older is increasing, according to demographic data published online ahead of print in the journal Addiction.

Researchers at New York University’s School of Medicine and at Columbia University evaluated marijuana use patterns for those over 50 years of age for the years 2006 to 2013.

Investigators reported that the prevalence of past-year cannabis use rose approximately…

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Studies: CBD Treatment Reduces Refractory Epileptic Seizures

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cannabidiol cbd

NORML | October 20, 2016

BOSTON, MA — Cannabidiol (CBD) administration is associated with the mitigation of treatment-resistant seizures, according to the findings of several recent clinical trials.

In one trial, investigators at Massachusetts General Hospital assessed CBD treatment over a 12-month period in 18 patients with refractory epileptic seizures due to Tuberous sclerosis complex (TSC). Researchers reported that CBD treatment reduced subjects’ median weekly seizure frequency by half. Authors concluded,…

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Study: Cannabis Inhalation Improves Parkinson’s Symptoms

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Study: Cannabis Inhalation Improves Parkinson’s Symptoms

Inhaling cannabis improves symptoms of Parkinson’s disease, according to clinical data published online ahead of print in the European Journal of Pain.

Investigators at Tel Aviv University and the Rabin Medical Center in Israel assessed the impact of cannabis exposure on motor symptoms and pain parameters in patients with Parkinson’s disease.

Researchers reported that cannabis inhalation was associated with improved symptoms 30-minutes following exposure. “Cannabis improved motor scores and pain symptoms in PD patients,” authors…

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Study: Medical Marijuana Laws Associated With Greater Workforce Participation Among Older Americans

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Study: Medical Marijuana Laws Associated With Greater Workforce Participation Among Older Americans

The enactment of statewide medicinal cannabis programs is associated with greater participation in the workforce by adults age 50 and older, according to the findings of a working paper published by the National Bureau of Economic Research, a non-partisan think-tank.

Researchers at the John Hopkins School of Public Health in Baltimore and Temple University in Philadelphia analyzed two-decades of data from the Health and Retirement Study, a nationally representative panel survey of Americans over 50 and their spouses, to determine the impact…

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Study: Opioid Prevalence Falls Following Medical Cannabis Legalization

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Study: Opioid Prevalence Falls Following Medical Cannabis Legalization

The implementation of medical marijuana programs is associated with a decrease in the prevalence of opioids detected among fatally injured drivers, according to data published in the American Journal of Public Health.

Researchers at Columbia University in New York and the University of California at Davis performed a between-state comparison of opioid positivity rates in fatal car accidents in 18 states. Authors reported that drivers between the ages of 21 and 40 who resided in states that permitted medical marijuana use were approximately…

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Study: Marijuana Use Linked to Lower BMI

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Study: Marijuana Use Linked to Lower BMI

CORAL GABLES, FL — Cannabis use is associated with lower body mass index (BMI) over time, according to data published in The Journal of Mental Health Policy and Economics.

Investigators at the University of Miami assessed the relationship between marijuana use and BMI in a nationally representative longitudinal sample (The National Longitudinal Study of Adolescent to Adult Health).

Researchers concluded, “[D]aily female marijuana users have a BMI that is approximately 3.1 percent lower than that of non-users, whereas daily male users have…

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Study: Epileptic Patients Report Subjective Benefits from Cannabis

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Study: Epileptic Patients Report Subjective Benefits from Cannabis

ONTARIO, CANADA — Patients with epilepsy frequently experiment with cannabis and most report experiencing subjective benefits following their use of the substance, according to data published online ahead of print in the journal Epilepsy & Behavior.

Canadian researchers surveyed the experiences of over 300 adult patients admitted to an epilepsy monitoring unit over a 14-month period. More than half of the respondents acknowledged having tried cannabis and over a third reported having used it in the past year.

Cannabis use was associated…

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Study: Cannabis Dosing Influences Pain Sensitivity

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Study: Cannabis Dosing Influences Pain Sensitivity

NEW YORK, NY — Cannabis inhalation influences subjects’ sensitivity to pain, according to clinical data published online ahead of print in the journal Drug and Alcohol Dependence.

Investigators at the Columbia University Medical Center in New York assessed the effects of cannabis versus placebo in subjects exposed to a laboratory-induced pain model. Participants in the trial immersed one of their hands in cold water. Researchers assessed subjects’ pain sensitivity and pain tolerance based on he length of time they were willing to keep…

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Study: Oral THC Safe and Effective for Treatment of Spasticity in Pediatric Patients

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Study: Oral THC Safe and Effective for Treatment of Spasticity in Pediatric Patients

DUSSELDORF, GERMANY — The administration of oral, synthetic THC (dronabinol) is safe and effective for the treatment of refractory spasticity in pediatric patients, according to clinical data published online ahead of print in the European Journal of Pediatric Neurology.

Researchers from the University of Dusseldorf in Germany assessed the palliative treatment of dronabinol in 16 adolescent subjects with complex neurological conditions. Subjects received dosing twice daily and the median duration of treatment was 181 days.

Oral THC…

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Case Report: Cannabinoid Extracts Safe and Effective in Tourette Syndrome Patient

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Case Report: Cannabinoid Extracts Safe and Effective in Tourette Syndrome Patient

TAURANGA, NEW ZEALAND — The administration of standardized cannabinoid extracts (Sativex) is safe and effective at mitigating symptoms of Tourette syndrome, according to a case report published online ahead of print in the journal Australasian Psychiatry.

Investigators at the Tauranga Hospital, Department of Psychiatry in New Zealand evaluated the impact of twice-daily Sativex administration in a patient with treatment-resistant Tourette syndrome (TS). Sativex is a spray containing an equal 1:1 ratio of THC to cannabidiol (CBD).

Following…

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Study: Marijuana Use Not Associated With Adverse Outcomes In Transplant Patients

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Study: Marijuana Use Not Associated With Adverse Outcomes In Transplant Patients

BALTIMORE, MD — A history of marijuana use is not contraindicated in kidney transplantation, according to data published online ahead of print in the journal Clinical Transplantation.

Researchers at the University of Maryland School of Medicine evaluated the association between marijuana use and treatment outcomes in 1,225 kidney recipients from 2008 to 2013. Compared to non-users, those patients who tested positive for cannabis experienced no greater risk of adverse outcomes after one year.

“[R]ecreational marijuana use should not be…

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Study: THC and CBDA Effective in Treating Nausea, Stimulating Appetite in Chemotherapy Patients

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Study: THC and CBDA Effective in Treating Nausea, Stimulating Appetite in Chemotherapy Patients

The administration of small amounts of tetrahydrocannabinol (THC) and cannabidiolic acid (CBD-A) may be effective in treating nausea and stimulating appetite in chemotherapy patients, according to the results of a new study.

Researchers found that the “administration of subthreshold doses of THC (0.5 and 1 mg/kg) or CBDA (0.5 and 1 μg/kg) significantly suppressed acute nausea-induced gaping, whereas higher individual doses of both THC and CBDA were maximally effective ” for acute nausea.

Combined administration of higher doses of…

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Study: More Young People Perceive Marijuana to be Harmful Following Passage of Medical Marijuana Laws

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Study: More Young People Perceive Marijuana to be Harmful Following Passage of Medical Marijuana Laws

The enactment of medical marijuana laws is associated with an increase in the percentage of 8th graders perceiving the substance to be harmful, according to survey data published online ahead of print in the journal Addiction.

A team of investigators from Columbia University, the University of California at Davis, the University of Michigan, and Boston University evaluated whether students’ perceptions of marijuana had changed following the legalization of medical cannabis in their states.

Authors reported that the passage of medical…

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Teen Pot Use Not Increased by Medical Marijuana Dispensaries

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Teen Pot Use Not Increased by Medical Marijuana Dispensaries

SAN DIEGO, CA — The availability of medical marijuana dispensaries is not positively associated with an increase in the number of adolescents currently using cannabis, according to data published online ahead of print in the journal Preventive Medicine.

An investigator at the University of California, San Diego assessed the association between marijuana dispensaries and cannabis use habits among young people residing within a 25-mile radius. The author reported that adolescents’ proximity to dispensaries did not influence their current…

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Military Vets Strongly Support Medical Marijuana Access

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Military Vets Strongly Support Medical Marijuana Access

More than two in three military veterans say that medical cannabis should be legal, and 75 percent believe that VA physicians should be able to recommend marijuana therapy to eligible patients, according to the results of the 7th annual membership survey of Iraq and Afghanistan Veterans of America (IAVA).

Sixty-eight percent of respondents said they “support the legalization of medical marijuana in their state.” Only 20 percent oppose legalizing medical cannabis access.

Seventy-five percent of veterans “believe the VA should allow…