N-acetylcysteine shows early promise in reducing alcohol use in marijuana-dependent teens

An over-the-counter antioxidant known as N-acetylcysteine (NAC) is showing early promise at promoting abstinence from or reduced use of alcohol in marijuana-dependent adolescents, report researchers at the Medical University of South Carolina (MUSC) in the December 2016 Addictive Behaviors. In a cohort of treatment-engaged marijuana-dependent adolescents, reduced marijuana use was associated with reductions in alcohol use in the NAC-treated group, but not placebo group. NAC is believed to restore neuronal glutamate homeostasis disrupted by…

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